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Inhibition of cGAS–STING pathway alleviates neuroinflammation-induced retinal ganglion cell death after ischemia/reperfusion injury

Acute glaucoma is a vision-threatening disease characterized by a sudden elevation in intraocular pressure (IOP), followed by retinal ganglion cell (RGC) death. Cytosolic double-stranded DNA (dsDNA)—a damage-associated molecular pattern (DAMP) that triggers inflammation and immune responses—has been...

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Detalles Bibliográficos
Autores principales:	Wu, Xingdi, Yu, Naiji, Ye, Zifan, Gu, Yuxiang, Zhang, Chengshou, Chen, Min, Wang, Kaijun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10509212/ https://www.ncbi.nlm.nih.gov/pubmed/37726272 http://dx.doi.org/10.1038/s41419-023-06140-0

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