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The tumor microenvironment shows a hierarchy of cell-cell interactions dominated by fibroblasts

The tumor microenvironment (TME) is comprised of non-malignant cells that interact with each other and with cancer cells, critically impacting cancer biology. The TME is complex, and understanding it requires simplifying approaches. Here we provide an experimental-mathematical approach to decompose...

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Detalles Bibliográficos
Autores principales: Mayer, Shimrit, Milo, Tomer, Isaacson, Achinoam, Halperin, Coral, Miyara, Shoval, Stein, Yaniv, Lior, Chen, Pevsner-Fischer, Meirav, Tzahor, Eldad, Mayo, Avi, Alon, Uri, Scherz-Shouval, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10509226/
https://www.ncbi.nlm.nih.gov/pubmed/37726308
http://dx.doi.org/10.1038/s41467-023-41518-w