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Context-dependent perturbations in chromatin folding and the transcriptome by cohesin and related factors
Cohesin regulates gene expression through context-specific chromatin folding mechanisms such as enhancer–promoter looping and topologically associating domain (TAD) formation by cooperating with factors such as cohesin loaders and the insulation factor CTCF. We developed a computational workflow to...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10509244/ https://www.ncbi.nlm.nih.gov/pubmed/37726281 http://dx.doi.org/10.1038/s41467-023-41316-4 |