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Context-dependent perturbations in chromatin folding and the transcriptome by cohesin and related factors

Cohesin regulates gene expression through context-specific chromatin folding mechanisms such as enhancer–promoter looping and topologically associating domain (TAD) formation by cooperating with factors such as cohesin loaders and the insulation factor CTCF. We developed a computational workflow to...

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Detalles Bibliográficos
Autores principales: Nakato, Ryuichiro, Sakata, Toyonori, Wang, Jiankang, Nagai, Luis Augusto Eijy, Nagaoka, Yuya, Oba, Gina Miku, Bando, Masashige, Shirahige, Katsuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10509244/
https://www.ncbi.nlm.nih.gov/pubmed/37726281
http://dx.doi.org/10.1038/s41467-023-41316-4