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A robust normalized local filter to estimate compositional heterogeneity directly from cryo-EM maps
Cryo electron microscopy (cryo-EM) is used by biological research to visualize biomolecular complexes in 3D, but the heterogeneity of cryo-EM reconstructions is not easily estimated. Current processing paradigms nevertheless exert great effort to reduce flexibility and heterogeneity to improve the q...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10509264/ https://www.ncbi.nlm.nih.gov/pubmed/37726277 http://dx.doi.org/10.1038/s41467-023-41478-1 |