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Nuclear miR-150 enhances hepatic lipid accumulation by targeting RNA transcripts overlapping the PLIN2 promoter

Alcohol-associated liver disease is a prevalent chronic liver disease caused by excessive ethanol consumption. This study aims to investigate the role of miR-150 in regulating hepatic lipid homeostasis in alcoholic fatty liver (AFL). miR-150 was mainly distributed in the nucleus of hepatocytes and c...

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Detalles Bibliográficos
Autores principales: Luo, Jiao, Ji, Yanan, Chen, Ningning, Song, Ge, Zhou, Shuyue, Niu, Xuan, Yu, Dianke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10509351/
https://www.ncbi.nlm.nih.gov/pubmed/37736048
http://dx.doi.org/10.1016/j.isci.2023.107837