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Nonlinear Mixed Effects Modeling of Glucagon Kinetics in Healthy Subjects

OBJECTIVE: To date, the lack of a model of glucagon kinetics precluded the possibility of estimating and studying glucagon secretion in vivo, e.g., using deconvolution, as done for other hormones like insulin and C-peptide. Here, we used a nonlinear mixed effects technique to develop a robust popula...

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Bibliographic Details
Main Authors: Faggionato, Edoardo, Laurenti, Marcello C., Vella, Adrian, Man, Chiara Dalla
Format: Online Article Text
Language:English
Published: 2023
Subjects:
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10509356/
https://www.ncbi.nlm.nih.gov/pubmed/37030857
http://dx.doi.org/10.1109/TBME.2023.3262974