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Nonlinear Mixed Effects Modeling of Glucagon Kinetics in Healthy Subjects
OBJECTIVE: To date, the lack of a model of glucagon kinetics precluded the possibility of estimating and studying glucagon secretion in vivo, e.g., using deconvolution, as done for other hormones like insulin and C-peptide. Here, we used a nonlinear mixed effects technique to develop a robust popula...
Main Authors: | , , , |
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Format: | Online Article Text |
Language: | English |
Published: |
2023
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Subjects: | |
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10509356/ https://www.ncbi.nlm.nih.gov/pubmed/37030857 http://dx.doi.org/10.1109/TBME.2023.3262974 |