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Study protocol of IMAGINE-HD: Imaging iron accumulation and neuroinflammation with 7T-MRI + CSF in Huntington’s disease

INTRODUCTION: Strong evidence suggests a significant role for iron accumulation in the brain in addition to the well-documented neurodegenerative aspects of Huntington’s disease (HD). The putative mechanisms by which iron is linked to the HD pathogenesis are multiple, including oxidative stress, fer...

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Detalles Bibliográficos
Autores principales: van de Zande, Nadine Anniek, Bulk, Marjolein, Najac, Chloé, van der Weerd, Louise, de Bresser, Jeroen, Lewerenz, Jan, Ronen, Itamar, de Bot, Susanne Tamara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10509525/
https://www.ncbi.nlm.nih.gov/pubmed/37327706
http://dx.doi.org/10.1016/j.nicl.2023.103450