Inferring causal genes at type 2 diabetes GWAS loci through chromosome interactions in islet cells

Background: Resolving causal genes for type 2 diabetes at loci implicated by genome-wide association studies (GWAS) requires integrating functional genomic data from relevant cell types. Chromatin features in endocrine cells of the pancreatic islet are particularly informative and recent studies lev...

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Detalles Bibliográficos
Autores principales: Torres, Jason M., Sun, Han, Nylander, Vibe, Downes, Damien J., van de Bunt, Martijn, McCarthy, Mark I., Hughes, Jim R., Gloyn, Anna L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10509606/
https://www.ncbi.nlm.nih.gov/pubmed/37736013
http://dx.doi.org/10.12688/wellcomeopenres.18653.2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10509606/
https://www.ncbi.nlm.nih.gov/pubmed/37736013
http://dx.doi.org/10.12688/wellcomeopenres.18653.2

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