Cargando…

Lipid clearance and amyloid formation by serum amyloid A: exploring the links between beneficial and pathologic actions of an enigmatic protein

Serum amyloid A (SAA) is named after a life-threatening disease, yet this small evolutionarily conserved protein must have played a vital role in host defense. Most circulating SAA binds plasma lipoproteins and modulates their metabolism. However, this hardly justifies the rapid and dramatic SAA upr...

Descripción completa

Detalles Bibliográficos
Autores principales: Jayaraman, Shobini, Urdaneta, Angela, Bullitt, Esther, Fändrich, Marcus, Gursky, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10509712/
https://www.ncbi.nlm.nih.gov/pubmed/37604227
http://dx.doi.org/10.1016/j.jlr.2023.100429