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Generation of CHOPe003-A ESC line to study an ACTG2 variant affecting smooth muscle development and function

Dysfunction of visceral smooth muscle (“visceral myopathy”) impairs bowel, bladder, and uterine function. Symptoms of this life-threatening condition include massive intestinal distension with slow transit, vomiting, feeding intolerance, growth failure, poor bladder emptying, and difficult vaginal d...

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Detalles Bibliográficos
Autores principales: Hashmi, Sohaib K., Schneider, Sabine, Gagne, Alyssa L., Maguire, Jean Ann, Anderson, Sierra, Gadue, Paul, Heuckeroth, Robert O., French, Deborah L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10509821/
https://www.ncbi.nlm.nih.gov/pubmed/37643495
http://dx.doi.org/10.1016/j.scr.2023.103186