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EP2 inhibition restores myeloid metabolism and reverses cognitive decline

Nonsteroidal anti-inflammatory drugs alleviate pain and inflammation by inhibiting the cyclooxygenase pathway. This pathway has various downstream effects, some of which are beneficial. Prostaglandin E(2) is a key downstream product in the cyclooxygenase pathway that modulates inflammation. A correl...

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Detalles Bibliográficos
Autores principales: Lushington, Ryan, Camilli, Samuel, Pascual, Francisco, Lockey, Richard F., Kolliputi, Narasaiah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10509962/
https://www.ncbi.nlm.nih.gov/pubmed/37780795
http://dx.doi.org/10.1016/j.jacig.2023.100082