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EP2 inhibition restores myeloid metabolism and reverses cognitive decline
Nonsteroidal anti-inflammatory drugs alleviate pain and inflammation by inhibiting the cyclooxygenase pathway. This pathway has various downstream effects, some of which are beneficial. Prostaglandin E(2) is a key downstream product in the cyclooxygenase pathway that modulates inflammation. A correl...
Autores principales: | Lushington, Ryan, Camilli, Samuel, Pascual, Francisco, Lockey, Richard F., Kolliputi, Narasaiah |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10509962/ https://www.ncbi.nlm.nih.gov/pubmed/37780795 http://dx.doi.org/10.1016/j.jacig.2023.100082 |
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