Structure-Based Design of Small Imine Reductase Panels for Target Substrates

[Image: see text] Biocatalysis is important in the discovery, development, and manufacture of pharmaceuticals. However, the identification of enzymes for target transformations of interest requires major screening efforts. Here, we report a structure-based computational workflow to prioritize protei...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Yuqi, Rué Casamajo, Arnau, Finnigan, William, Schnepel, Christian, Barker, Rhys, Morrill, Charlotte, Heath, Rachel S., De Maria, Leonardo, Turner, Nicholas J., Scrutton, Nigel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10510103/
https://www.ncbi.nlm.nih.gov/pubmed/37736118
http://dx.doi.org/10.1021/acscatal.3c02278

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10510103/
https://www.ncbi.nlm.nih.gov/pubmed/37736118
http://dx.doi.org/10.1021/acscatal.3c02278

Ejemplares similares