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Structure-Based Design of Small Imine Reductase Panels for Target Substrates
[Image: see text] Biocatalysis is important in the discovery, development, and manufacture of pharmaceuticals. However, the identification of enzymes for target transformations of interest requires major screening efforts. Here, we report a structure-based computational workflow to prioritize protei...
Autores principales: | Yu, Yuqi, Rué Casamajo, Arnau, Finnigan, William, Schnepel, Christian, Barker, Rhys, Morrill, Charlotte, Heath, Rachel S., De Maria, Leonardo, Turner, Nicholas J., Scrutton, Nigel S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10510103/ https://www.ncbi.nlm.nih.gov/pubmed/37736118 http://dx.doi.org/10.1021/acscatal.3c02278 |
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