Cargando…

Direct Modulators of K-Ras–Membrane Interactions

[Image: see text] Protein–membrane interactions (PMIs) are ubiquitous in cellular signaling. Initial steps of signal transduction cascades often rely on transient and dynamic interactions with the inner plasma membrane leaflet to populate and regulate signaling hotspots. Methods to target and modula...

Descripción completa

Detalles Bibliográficos
Autores principales: Morstein, Johannes, Shrestha, Rebika, Van, Que N., López, César A., Arora, Neha, Tonelli, Marco, Liang, Hong, Chen, De, Zhou, Yong, Hancock, John F., Stephen, Andrew G., Turbyville, Thomas J., Shokat, Kevan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10510109/
https://www.ncbi.nlm.nih.gov/pubmed/37579045
http://dx.doi.org/10.1021/acschembio.3c00413