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Hyperoxia but not high tidal volume contributes to ventilator-induced lung injury in healthy mice

BACKGROUND: Mechanical ventilation is a supportive therapy used to maintain respiratory function in several clinical and surgical cases but is always accompanied by lung injury risk due to improper treatment. We investigated how tidal volume and oxygen delivery would contribute independently or syne...

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Detalles Bibliográficos
Autores principales: Xu, Yong, Li, Yu, Zhai, Da, Yan, Chen, Liang, Jingyan, Ichinomiya, Taiga, Hara, Tetsuya, Inadomi, Chiaki, Li, Tao-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10510264/
https://www.ncbi.nlm.nih.gov/pubmed/37730597
http://dx.doi.org/10.1186/s12890-023-02626-x