Brahma-related gene 1 acts as a profibrotic mediator and targeting it by micheliolide ameliorates peritoneal fibrosis

BACKGROUND: Progressive peritoneal fibrosis is a worldwide public health concern impacting patients undergoing peritoneal dialysis (PD), yet there is no effective treatment. Our previous study revealed that a novel compound, micheliolide (MCL) inhibited peritoneal fibrosis in mice. However, its mech...

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Detalles Bibliográficos
Autores principales: Li, Shuting, Luo, Congwei, Chen, Sijia, Zhuang, Yiyi, Ji, Yue, Zeng, Yiqun, Zeng, Yao, He, Xiaoyang, Xiao, Jing, Wang, Huizhen, Chen, Xiaowen, Long, Haibo, Peng, Fenfen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10510267/
https://www.ncbi.nlm.nih.gov/pubmed/37726857
http://dx.doi.org/10.1186/s12967-023-04469-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10510267/
https://www.ncbi.nlm.nih.gov/pubmed/37726857
http://dx.doi.org/10.1186/s12967-023-04469-w

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