Cargando…
Brahma-related gene 1 acts as a profibrotic mediator and targeting it by micheliolide ameliorates peritoneal fibrosis
BACKGROUND: Progressive peritoneal fibrosis is a worldwide public health concern impacting patients undergoing peritoneal dialysis (PD), yet there is no effective treatment. Our previous study revealed that a novel compound, micheliolide (MCL) inhibited peritoneal fibrosis in mice. However, its mech...
Autores principales: | Li, Shuting, Luo, Congwei, Chen, Sijia, Zhuang, Yiyi, Ji, Yue, Zeng, Yiqun, Zeng, Yao, He, Xiaoyang, Xiao, Jing, Wang, Huizhen, Chen, Xiaowen, Long, Haibo, Peng, Fenfen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10510267/ https://www.ncbi.nlm.nih.gov/pubmed/37726857 http://dx.doi.org/10.1186/s12967-023-04469-w |
Ejemplares similares
-
Micheliolide ameliorates renal fibrosis by suppressing the Mtdh/BMP/MAPK pathway
por: Peng, Fenfen, et al.
Publicado: (2019) -
Brahma-related gene-1 promotes tubular senescence and renal fibrosis through Wnt/β-catenin/autophagy axis
por: Gong, Wangqiu, et al.
Publicado: (2021) -
Correction: Micheliolide ameliorates renal fibrosis by suppressing the Mtdh/BMP/MAPK pathway
por: Peng, Fenfen, et al.
Publicado: (2019) -
Micheliolide Attenuates Lipopolysaccharide-Induced Inflammation by Modulating the mROS/NF-κB/NLRP3 Axis in Renal Tubular Epithelial Cells
por: Lei, Xianghong, et al.
Publicado: (2020) -
Micheliolide suppresses LPS-induced neuroinflammatory responses
por: Sun, Zhaomeng, et al.
Publicado: (2017)