Circulating cell-free DNA (cfDNA) in patients with medullary thyroid carcinoma is characterized by specific fragmentation and methylation changes with diagnostic value

Medullary Thyroid Carcinoma (MTC) is a rare neuroendocrine tumour whose diagnosis includes evaluating calcitonin serum levels, which can present fluctuations unrelated to MTC. Here, we investigated circulating DNA fragmentation and methylation changes as potential biomarkers using ddPCR on cell-free...

Descripción completa

Detalles Bibliográficos
Autores principales: Citarella, Anna, Besharat, Zein Mersini, Trocchianesi, Sofia, Autilio, Tanja Milena, Verrienti, Antonella, Catanzaro, Giuseppina, Splendiani, Elena, Spinello, Zaira, Cantara, Silvia, Zavattari, Patrizia, Loi, Eleonora, Romei, Cristina, Ciampi, Raffaele, Pezzullo, Luciano, Castagna, Maria Grazia, Angeloni, Antonio, Elisei, Rosella, Durante, Cosimo, Po, Agnese, Ferretti, Elisabetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Correspondence
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10510276/
https://www.ncbi.nlm.nih.gov/pubmed/37726827
http://dx.doi.org/10.1186/s40364-023-00522-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10510276/
https://www.ncbi.nlm.nih.gov/pubmed/37726827
http://dx.doi.org/10.1186/s40364-023-00522-4

Ejemplares similares