Regulation of the hippocampal translatome by Apoer2-ICD release

BACKGROUND: ApoE4, the most significant genetic risk factor for late-onset Alzheimer’s disease (AD), sequesters a pro-synaptogenic Reelin receptor, Apoer2, in the endosomal compartment and prevents its normal recycling. In the adult brain, Reelin potentiates excitatory synapses and thereby protects...

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Detalles Bibliográficos
Autores principales: Wasser, Catherine R., Werthmann, Gordon C., Hall, Eric M., Kuhbandner, Kristina, Wong, Connie H., Durakoglugil, Murat S., Herz, Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10510282/
https://www.ncbi.nlm.nih.gov/pubmed/37726747
http://dx.doi.org/10.1186/s13024-023-00652-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10510282/
https://www.ncbi.nlm.nih.gov/pubmed/37726747
http://dx.doi.org/10.1186/s13024-023-00652-1

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