Cargando…

Regulation of the hippocampal translatome by Apoer2-ICD release

BACKGROUND: ApoE4, the most significant genetic risk factor for late-onset Alzheimer’s disease (AD), sequesters a pro-synaptogenic Reelin receptor, Apoer2, in the endosomal compartment and prevents its normal recycling. In the adult brain, Reelin potentiates excitatory synapses and thereby protects...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wasser, Catherine R., Werthmann, Gordon C., Hall, Eric M., Kuhbandner, Kristina, Wong, Connie H., Durakoglugil, Murat S., Herz, Joachim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10510282/ https://www.ncbi.nlm.nih.gov/pubmed/37726747 http://dx.doi.org/10.1186/s13024-023-00652-1

Ejemplares similares

Apoer2-ICD-dependent regulation of hippocampal ribosome mRNA loading
por: Wasser, Catherine, et al.
Publicado: (2023)

Reelin Regulates Neuronal Excitability through Striatal-Enriched Protein Tyrosine Phosphatase (STEP(61)) and Calcium Permeable AMPARs in an NMDAR-Dependent Manner
por: Durakoglugil, Murat S., et al.
Publicado: (2021)

The Reelin Receptors Apoer2 and Vldlr Coordinate the Patterning of Purkinje Cell Topography in the Developing Mouse Cerebellum
por: Larouche, Matt, et al.
Publicado: (2008)

NHE6 depletion corrects ApoE4-mediated synaptic impairments and reduces amyloid plaque load
por: Pohlkamp, Theresa, et al.
Publicado: (2021)

Structural basis for ligand capture and release by the endocytic receptor ApoER2
por: Hirai, Hidenori, et al.
Publicado: (2017)

ApoER2: Functional Tuning Through Splicing
por: Gallo, Christina M., et al.
Publicado: (2020)

VLDLR and ApoER2 are receptors for multiple alphaviruses
por: Clark, Lars E., et al.
Publicado: (2021)

NGP 555, a γ-secretase modulator, shows a beneficial shift in the ratio of amyloid biomarkers in human cerebrospinal fluid at safe doses
por: Kounnas, Maria Z., et al.
Publicado: (2019)

Reversal of ApoE4-induced recycling block as a novel prevention approach for Alzheimer’s disease
por: Xian, Xunde, et al.
Publicado: (2018)

Sorting Nexin 17 Regulates ApoER2 Recycling and Reelin Signaling
por: Sotelo, Pablo, et al.
Publicado: (2014)

Reelin Together with ApoER2 Regulates Interneuron Migration in the Olfactory Bulb
por: Hellwig, Sabine, et al.
Publicado: (2012)

Similarities and differences in structure, expression, and functions of VLDLR and ApoER2
por: Reddy, Sunil S, et al.
Publicado: (2011)

ApoER2 trafficking, processing and signaling and its participation in neurodegeneration
por: Marzolo, María-Paz
Publicado: (2012)

Reelin and its receptors, VLDLR and ApoER2, in melanocytic nevi
por: Mihail, A, et al.
Publicado: (2017)

Neurotrophins regulate ApoER2 proteolysis through activation of the Trk signaling pathway
por: Larios, Jorge A, et al.
Publicado: (2014)

Capture, Release, and Identification of Newly Synthesized Proteins for Improved Profiling of Functional Translatomes
por: Phillips, Nancy J., et al.
Publicado: (2023)

Translatomics: The Global View of Translation
por: Zhao, Jing, et al.
Publicado: (2019)

Insights Into Translatomics in the Nervous System
por: Zhang, Shuxia, et al.
Publicado: (2020)

Lrp4 Domains Differentially Regulate Limb/Brain Development and Synaptic Plasticity
por: Pohlkamp, Theresa, et al.
Publicado: (2015)

TranslatomeDB: a comprehensive database and cloud-based analysis platform for translatome sequencing data
por: Liu, Wanting, et al.
Publicado: (2018)

Translatome Regulation in Neuronal Injury and Axon Regrowth
por: Rozenbaum, Meir, et al.
Publicado: (2018)

Splicing therapeutics for Alzheimer's disease
por: Wasser, Catherine R, et al.
Publicado: (2016)

Effects of Kasugamycin on the Translatome of Escherichia coli
por: Lange, Christian, et al.
Publicado: (2017)

Data on translatome analysis of Mycoplasma gallisepticum
por: Fisunov, G.Y., et al.
Publicado: (2016)

Transcriptome and translatome co-evolution in mammals
por: Wang, Zhong-Yi, et al.
Publicado: (2020)

The Reelin Receptors Apolipoprotein E receptor 2 (ApoER2) and VLDL Receptor
por: Dlugosz, Paula, et al.
Publicado: (2018)

The pathogenesis of mesothelioma is driven by a dysregulated translatome
por: Grosso, Stefano, et al.
Publicado: (2021)

Polysome Fractionation and Analysis of Mammalian Translatomes on a Genome-wide Scale
por: Gandin, Valentina, et al.
Publicado: (2014)

Reelin-dependent ApoER2 downregulation uncouples newborn neurons from progenitor cells
por: Pérez-Martínez, F. Javier, et al.
Publicado: (2012)

Therapeutic correction of ApoER2 splicing in Alzheimer's disease mice using antisense oligonucleotides
por: Hinrich, Anthony J, et al.
Publicado: (2016)

The E3 ubiquitin ligase IDOL regulates synaptic ApoER2 levels and is important for plasticity and learning
por: Gao, Jie, et al.
Publicado: (2017)

Stress-Dependent Coordination of Transcriptome and Translatome in Yeast
por: Halbeisen, Regula E, et al.
Publicado: (2009)

Tissue- and stage-specific landscape of the mouse translatome
por: Wang, Hongwei, et al.
Publicado: (2021)

The translatome of neuronal cell bodies, dendrites, and axons
por: Glock, Caspar, et al.
Publicado: (2021)

Selection of Cashmere Fineness Functional Genes by Translatomics
por: Zhang, Yu, et al.
Publicado: (2022)

Functional Roles of the Interaction of APP and Lipoprotein Receptors
por: Pohlkamp, Theresa, et al.
Publicado: (2017)

Large-scale translatome profiling annotates the functional genome and reveals the key role of genic 3′ untranslated regions in translatomic variation in plants
por: Zhu, Wanchao, et al.
Publicado: (2021)

Correction: Stress-Dependent Coordination of Transcriptome and Translatome in Yeast
por: Halbeisen, Regula E, et al.
Publicado: (2012)

Digital expression profiling of the compartmentalized translatome of Purkinje neurons
por: Kratz, Anton, et al.
Publicado: (2014)

Translatome analysis at the egg-to-embryo transition in sea urchin
por: Chassé, Héloïse, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_ihb3tofufa9olri77ujk76dgkm