DISCERN: deep single-cell expression reconstruction for improved cell clustering and cell subtype and state detection

BACKGROUND: Single-cell sequencing provides detailed insights into biological processes including cell differentiation and identity. While providing deep cell-specific information, the method suffers from technical constraints, most notably a limited number of expressed genes per cell, which leads t...

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Detalles Bibliográficos
Autores principales: Hausmann, Fabian, Ergen, Can, Khatri, Robin, Marouf, Mohamed, Hänzelmann, Sonja, Gagliani, Nicola, Huber, Samuel, Machart, Pierre, Bonn, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10510283/
https://www.ncbi.nlm.nih.gov/pubmed/37730638
http://dx.doi.org/10.1186/s13059-023-03049-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10510283/
https://www.ncbi.nlm.nih.gov/pubmed/37730638
http://dx.doi.org/10.1186/s13059-023-03049-x

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