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DISCERN: deep single-cell expression reconstruction for improved cell clustering and cell subtype and state detection
BACKGROUND: Single-cell sequencing provides detailed insights into biological processes including cell differentiation and identity. While providing deep cell-specific information, the method suffers from technical constraints, most notably a limited number of expressed genes per cell, which leads t...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10510283/ https://www.ncbi.nlm.nih.gov/pubmed/37730638 http://dx.doi.org/10.1186/s13059-023-03049-x |