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Dual inhibition of glycolysis and glutaminolysis for synergistic therapy of rheumatoid arthritis

BACKGROUND: Synovial fibroblasts in rheumatoid arthritis (RAFLS) exhibit a pathological aberration of glycolysis and glutaminolysis. Henceforth, we aimed to investigate if dual inhibition of these pathways by phytobiological compound c28MS has the potential of synergistic therapy for arthritis by ta...

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Detalles Bibliográficos
Autores principales: Ahmed, Shanzay, Mahony, Christopher B., Torres, Alyssa, Murillo-Saich, Jessica, Kemble, Samuel, Cedeno, Martha, John, Peter, Bhatti, Attya, Croft, Adam P., Guma, Monica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10510293/
https://www.ncbi.nlm.nih.gov/pubmed/37730663
http://dx.doi.org/10.1186/s13075-023-03161-0