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The Transition from Unfolded to Folded G-Quadruplex DNA Analyzed and Interpreted by Two-Dimensional Infrared Spectroscopy

[Image: see text] A class of DNA folds/structures known collectively as G-quadruplexes (G4) commonly forms in guanine-rich areas of genomes. G4-DNA is thought to have a functional role in the regulation of gene transcription and telomerase-mediated telomere maintenance and, therefore, is a target fo...

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Detalles Bibliográficos
Autores principales: Soenarjo, A. Larasati, Lan, Zhihao, Sazanovich, Igor V., Chan, Yee San, Ringholm, Magnus, Jha, Ajay, Klug, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10510320/
https://www.ncbi.nlm.nih.gov/pubmed/37647128
http://dx.doi.org/10.1021/jacs.3c04044