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A Biomimetic C-Terminal Extension Strategy for Photocaging Amidated Neuropeptides

[Image: see text] Photoactivatable neuropeptides offer a robust stimulus–response relationship that can drive mechanistic studies into the physiological mechanisms of neuropeptidergic transmission. The majority of neuropeptides contain a C-terminal amide, which offers a potentially general site for...

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Detalles Bibliográficos
Autores principales: Layden, Aryanna E., Ma, Xiang, Johnson, Caroline A., He, Xinyi J., Buczynski, Stanley A., Banghart, Matthew R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10510324/
https://www.ncbi.nlm.nih.gov/pubmed/37649440
http://dx.doi.org/10.1021/jacs.3c03913