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The nuclear receptor LRH‐1 discriminates between ligands using distinct allosteric signaling circuits

Nuclear receptors (NRs) are transcription factors that regulate essential biological processes in response to cognate ligands. An important part of NR function involves ligand‐induced conformational changes that recruit coregulator proteins to the activation function surface (AFS), ~15 Å away from t...

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Detalles Bibliográficos
Autores principales:	Mays, Suzanne G., Hercules, David, Ortlund, Eric A., Okafor, C. Denise
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Inc. 2023
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10510465/ https://www.ncbi.nlm.nih.gov/pubmed/37572334 http://dx.doi.org/10.1002/pro.4754

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