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Stanniocalcin‐2 inhibits skeletal muscle growth and is upregulated in functional overload‐induced hypertrophy
AIMS: Stanniocalcin‐2 (STC2) has recently been implicated in human muscle mass variability by genetic analysis. Biochemically, STC2 inhibits the proteolytic activity of the metalloproteinase PAPP‐A, which promotes muscle growth by upregulating the insulin‐like growth factor (IGF) axis. The aim was t...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10510475/ https://www.ncbi.nlm.nih.gov/pubmed/37568262 http://dx.doi.org/10.14814/phy2.15793 |