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Stanniocalcin‐2 inhibits skeletal muscle growth and is upregulated in functional overload‐induced hypertrophy

AIMS: Stanniocalcin‐2 (STC2) has recently been implicated in human muscle mass variability by genetic analysis. Biochemically, STC2 inhibits the proteolytic activity of the metalloproteinase PAPP‐A, which promotes muscle growth by upregulating the insulin‐like growth factor (IGF) axis. The aim was t...

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Detalles Bibliográficos
Autores principales: Lionikas, Arimantas, Hernandez Cordero, Ana I., Kilikevicius, Audrius, Carroll, Andrew M., Bewick, Guy S., Bunger, Lutz, Ratkevicius, Aivaras, Heisler, Lora K., Harboe, Mette, Oxvig, Claus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10510475/
https://www.ncbi.nlm.nih.gov/pubmed/37568262
http://dx.doi.org/10.14814/phy2.15793