Preparation and physicochemical characterization of N-succinyl chitosan-coated liposomes for oral delivery of grape seed extract and evaluation of its effect on pulmonary fibrosis induced by bleomycin in rats

OBJECTIVE(S): This study aimed to develop an oral succinyl chitosan-coated liposomal formulation containing grape seed extract and assess its therapeutic efficacy in rats with bleomycin-induced pulmonary fibrosis. MATERIALS AND METHODS: N-succinyl chitosan was synthesized, and the liposomal formulat...

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Detalles Bibliográficos
Autores principales: Bavarsad, Neda, Hemmati, Ali Asghar, Jafarian, Fateme, Mostoufi, Azar, Siahpoosh, Amir, Rashidi Nooshabadi, Mohammadreza, Mansouri, Esrafil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10510488/
https://www.ncbi.nlm.nih.gov/pubmed/37736512
http://dx.doi.org/10.22038/IJBMS.2023.70797.15381

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10510488/
https://www.ncbi.nlm.nih.gov/pubmed/37736512
http://dx.doi.org/10.22038/IJBMS.2023.70797.15381

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