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Preparation and physicochemical characterization of N-succinyl chitosan-coated liposomes for oral delivery of grape seed extract and evaluation of its effect on pulmonary fibrosis induced by bleomycin in rats
OBJECTIVE(S): This study aimed to develop an oral succinyl chitosan-coated liposomal formulation containing grape seed extract and assess its therapeutic efficacy in rats with bleomycin-induced pulmonary fibrosis. MATERIALS AND METHODS: N-succinyl chitosan was synthesized, and the liposomal formulat...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Mashhad University of Medical Sciences
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10510488/ https://www.ncbi.nlm.nih.gov/pubmed/37736512 http://dx.doi.org/10.22038/IJBMS.2023.70797.15381 |