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Targeted delivery of doxorubicin and therapeutic FOXM1 aptamer to tumor cells using gold nanoparticles modified with AS1411 and ATP aptamers

OBJECTIVE(S): A targeted delivery platform was prepared to co-deliver both doxorubicin (Dox) as an anticancer drug and FOXM1 aptamer as a therapeutic substance to breast cancer cells (4T1 and MCF-7) to reduce Dox side effects and increase its therapeutic efficacy. The targeted system (AuNPs-AFPA) co...

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Detalles Bibliográficos
Autores principales: Abdollahzade, Aref, Rahimi, Hoda, Yaghoobi, Elnaz, Ramezani, Mohammad, Alibolandi, Mona, Abnous, Khalil, Taghdisi, Seyed Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10510489/
https://www.ncbi.nlm.nih.gov/pubmed/37736517
http://dx.doi.org/10.22038/IJBMS.2023.71129.15452