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Costunolide prevents renal ischemia-reperfusion injury in rats by reducing autophagy, apoptosis, inflammation, and DNA damage

OBJECTIVE(S): Renal ischemia-reperfusion (I/R) is a vital health condition leading to acute kidney injury. Costunolide (COST) is an actively used molecule clinically for its anti-inflammatory, antioxidant, and immunomodulatory properties. In the present study, we searched for the possible protective...

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Detalles Bibliográficos
Autores principales: Güler, Mustafa Can, Akpinar, Erol, Tanyeli, Ayhan, Çomakli, Selim, Bayir, Yasin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10510491/
https://www.ncbi.nlm.nih.gov/pubmed/37736519
http://dx.doi.org/10.22038/IJBMS.2023.71779.15596