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Human Immunodeficiency Virus 1 Preferentially Fuses with pH-Neutral Endocytic Vesicles in Cell Lines and Human Primary CD4+ T-Cells

[Image: see text] Despite extensive efforts, the principal sites of productive HIV-1 entry in different target cells—plasma membrane (PM) vs endosomes—remain controversial. To delineate the site(s) of HIV-1 fusion, we implemented a triple labeling approach that involves tagging pseudoviruses with th...

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Detalles Bibliográficos
Autores principales: Sharma, Manish, Marin, Mariana, Wu, Hui, Prikryl, David, Melikyan, Gregory B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10510587/
https://www.ncbi.nlm.nih.gov/pubmed/37589658
http://dx.doi.org/10.1021/acsnano.3c05508