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Structural advances toward understanding the catalytic activity and conformational dynamics of modular nonribosomal peptide synthetases

Covering: up to fall 2022. Nonribosomal peptide synthetases (NRPSs) are a family of modular, multidomain enzymes that catalyze the biosynthesis of important peptide natural products, including antibiotics, siderophores, and molecules with other biological activity. The NRPS architecture involves an...

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Detalles Bibliográficos
Autores principales: Patel, Ketan D., MacDonald, Monica R., Ahmed, Syed Fardin, Singh, Jitendra, Gulick, Andrew M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10510592/
https://www.ncbi.nlm.nih.gov/pubmed/37114973
http://dx.doi.org/10.1039/d3np00003f