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Synthesis of Functionalized Pyrrolidinone Scaffolds via Smiles-Truce Cascade
[Image: see text] Arylsulfonamides have been found to react with cyclopropane diesters under simple base treatment to give α-arylated pyrrolidinones. This one-pot process comprises three steps: nucleophilic ring-opening of the cyclopropane, reaction of the resulting enolate in a Smiles-Truce aryl tr...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10510726/ https://www.ncbi.nlm.nih.gov/pubmed/37668613 http://dx.doi.org/10.1021/acs.orglett.3c02559 |