Short and Efficient Synthesis of the Antituberculosis Agent Pretomanid from (R)-Glycidol

[Image: see text] An efficient gram-scale synthesis of the antituberculosis agent pretomanid using straightforward chemistry, mild reaction conditions, and readily available starting materials is reported. Four different protecting groups on the glycidol moiety were investigated for their technical...

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Detalles Bibliográficos
Autores principales: Lucas, Tobias, Dietz, Jule-Philipp, Cardoso, Flavio S. P., Snead, David R., Nelson, Ryan C., Donsbach, Kai O., Gupton, B. Frank, Opatz, Till
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10510727/
https://www.ncbi.nlm.nih.gov/pubmed/37736135
http://dx.doi.org/10.1021/acs.oprd.3c00187

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10510727/
https://www.ncbi.nlm.nih.gov/pubmed/37736135
http://dx.doi.org/10.1021/acs.oprd.3c00187

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