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C(sp(2))–H cyclobutylation of hydroxyarenes enabled by silver-π-acid catalysis: diastereocontrolled synthesis of 1,3-difunctionalized cyclobutanes

Ring-opening of bicyclo[1.1.0]butanes (BCBs) is emerging as a powerful strategy for 1,3-difunctionalized cyclobutane synthesis. However, reported radical strain-release reactions are typically plagued with diastereoselectivity issues. Herein, an atom-economic protocol for the highly chemo- and diast...

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Detalles Bibliográficos
Autores principales: Tang, Lei, Huang, Qi-Nan, Wu, Feng, Xiao, Yuanjiu, Zhou, Jin-Lan, Xu, Tong-Tong, Wu, Wen-Biao, Qu, Shuanglin, Feng, Jian-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10510764/
https://www.ncbi.nlm.nih.gov/pubmed/37736637
http://dx.doi.org/10.1039/d3sc03258b