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Time-course transcriptome analysis of a double challenge bleomycin-induced lung fibrosis rat model uncovers ECM homoeostasis-related translationally relevant genes

BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is an irreversible disorder with a poor prognosis. The incomplete understanding of IPF pathogenesis and the lack of accurate animal models is limiting the development of effective treatments. Thus, the selection of clinically relevant animal models end...

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Detalles Bibliográficos
Autores principales: Bonatti, Martina, Pitozzi, Vanessa, Caruso, Paola, Pontis, Silvia, Pittelli, Maria Gloria, Frati, Caterina, Mangiaracina, Chiara, Lagrasta, Costanza Anna Maria, Quaini, Federico, Cantarella, Simona, Ottonello, Simone, Villetti, Gino, Civelli, Maurizio, Montanini, Barbara, Trevisani, Marcello
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10510891/
https://www.ncbi.nlm.nih.gov/pubmed/37730279
http://dx.doi.org/10.1136/bmjresp-2022-001476