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Time-course transcriptome analysis of a double challenge bleomycin-induced lung fibrosis rat model uncovers ECM homoeostasis-related translationally relevant genes
BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is an irreversible disorder with a poor prognosis. The incomplete understanding of IPF pathogenesis and the lack of accurate animal models is limiting the development of effective treatments. Thus, the selection of clinically relevant animal models end...
Autores principales: | Bonatti, Martina, Pitozzi, Vanessa, Caruso, Paola, Pontis, Silvia, Pittelli, Maria Gloria, Frati, Caterina, Mangiaracina, Chiara, Lagrasta, Costanza Anna Maria, Quaini, Federico, Cantarella, Simona, Ottonello, Simone, Villetti, Gino, Civelli, Maurizio, Montanini, Barbara, Trevisani, Marcello |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10510891/ https://www.ncbi.nlm.nih.gov/pubmed/37730279 http://dx.doi.org/10.1136/bmjresp-2022-001476 |
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