Myeloblasts transition to megakaryoblastic immunophenotypes over time in some patients with myelodysplastic syndromes

OBJECTIVES: In myelodysplastic syndromes (MDS), neoplastic myeloblast (CD34+CD13+CD33+ cells) numbers often increase over time, leading to secondary acute myeloid leukemia (AML). In recent studies, blasts in some MDS patients have been found to express a megakaryocyte-lineage molecule, CD41, and suc...

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Detalles Bibliográficos
Autores principales: Ogata, Kiyoyuki, Mochimaru, Yuto, Sei, Kazuma, Kawahara, Naoya, Ogata, Mika, Yamamoto, Yumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10511088/
https://www.ncbi.nlm.nih.gov/pubmed/37729123
http://dx.doi.org/10.1371/journal.pone.0291662

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10511088/
https://www.ncbi.nlm.nih.gov/pubmed/37729123
http://dx.doi.org/10.1371/journal.pone.0291662

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