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Myeloblasts transition to megakaryoblastic immunophenotypes over time in some patients with myelodysplastic syndromes

OBJECTIVES: In myelodysplastic syndromes (MDS), neoplastic myeloblast (CD34+CD13+CD33+ cells) numbers often increase over time, leading to secondary acute myeloid leukemia (AML). In recent studies, blasts in some MDS patients have been found to express a megakaryocyte-lineage molecule, CD41, and suc...

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Detalles Bibliográficos
Autores principales:	Ogata, Kiyoyuki, Mochimaru, Yuto, Sei, Kazuma, Kawahara, Naoya, Ogata, Mika, Yamamoto, Yumi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10511088/ https://www.ncbi.nlm.nih.gov/pubmed/37729123 http://dx.doi.org/10.1371/journal.pone.0291662

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