Replication cycle timing determines phage sensitivity to a cytidine deaminase toxin/antitoxin bacterial defense system

Toxin-antitoxin (TA) systems are ubiquitous two-gene loci that bacteria use to regulate cellular processes such as phage defense. Here, we demonstrate the mechanism by which a novel type III TA system, avcID, is activated and confers resistance to phage infection. The toxin of the system (AvcD) is a...

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Detalles Bibliográficos
Autores principales: Hsueh, Brian Y., Ferrell, Micah J., Sanath-Kumar, Ram, Bedore, Amber M., Waters, Christopher M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10511110/
https://www.ncbi.nlm.nih.gov/pubmed/37683045
http://dx.doi.org/10.1371/journal.ppat.1011195

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10511110/
https://www.ncbi.nlm.nih.gov/pubmed/37683045
http://dx.doi.org/10.1371/journal.ppat.1011195

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