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Replication cycle timing determines phage sensitivity to a cytidine deaminase toxin/antitoxin bacterial defense system
Toxin-antitoxin (TA) systems are ubiquitous two-gene loci that bacteria use to regulate cellular processes such as phage defense. Here, we demonstrate the mechanism by which a novel type III TA system, avcID, is activated and confers resistance to phage infection. The toxin of the system (AvcD) is a...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10511110/ https://www.ncbi.nlm.nih.gov/pubmed/37683045 http://dx.doi.org/10.1371/journal.ppat.1011195 |