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Discovery of neutralizing SARS-CoV-2 antibodies enriched in a unique antigen specific B cell cluster

Despite development of effective SARS-CoV-2 vaccines, a sub-group of vaccine non-responders depends on therapeutic antibodies or small-molecule drugs in cases of severe disease. However, perpetual viral evolution has required continuous efficacy monitoring as well as exploration of new therapeutic a...

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Detalles Bibliográficos
Autores principales: Lende, Stine Sofie Frank, Barnkob, Nanna Møller, Hansen, Randi Westh, Bansia, Harsh, Vestergaard, Mike, Rothemejer, Frederik Holm, Worsaae, Anne, Brown, Deijona, Pedersen, Maria Lange, Rahimic, Anna Halling Folkmar, Juhl, Anna Karina, Gjetting, Torben, Østergaard, Lars, Georges, Amédée Des, Vuillard, Laurent-Michel, Schleimann, Mariane Høgsbjerg, Koefoed, Klaus, Tolstrup, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10511142/
https://www.ncbi.nlm.nih.gov/pubmed/37729215
http://dx.doi.org/10.1371/journal.pone.0291131