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Cholesterol depletion decreases adhesion of non-small cell lung cancer cells to E-selectin

Lipid microdomains, ordered membrane phases containing cholesterol and glycosphingolipids, play an essential role in cancer cell adhesion and ultimately metastasis. Notably, elevated levels of cholesterol-rich lipid microdomains are found in cancer cells relative to their normal counterparts. Theref...

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Detalles Bibliográficos
Autores principales: Mohammadalipour, Amina, Showalter, Christian A., Muturi, Harrison T., Farnoud, Amir M., Najjar, Sonia M., Burdick, Monica M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10511166/
https://www.ncbi.nlm.nih.gov/pubmed/37399498
http://dx.doi.org/10.1152/ajpcell.00197.2020