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Central role of Tim17 in mitochondrial presequence protein translocation

The presequence translocase of the mitochondrial inner membrane (TIM23) represents the major route for the import of nuclear-encoded proteins into mitochondria(1,2). About 60% of more than 1,000 different mitochondrial proteins are synthesized with amino-terminal targeting signals, termed presequenc...

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Detalles Bibliográficos
Autores principales: Fielden, Laura F., Busch, Jakob D., Merkt, Sandra G., Ganesan, Iniyan, Steiert, Conny, Hasselblatt, Hanna B., Busto, Jon V., Wirth, Christophe, Zufall, Nicole, Jungbluth, Sibylle, Noll, Katja, Dung, Julia M., Butenko, Ludmila, von der Malsburg, Karina, Koch, Hans-Georg, Hunte, Carola, van der Laan, Martin, Wiedemann, Nils
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10511324/
https://www.ncbi.nlm.nih.gov/pubmed/37527780
http://dx.doi.org/10.1038/s41586-023-06477-8