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Colocalization of expression transcripts with COVID-19 outcomes is rare across cell states, cell types and organs
Identifying causal genes at GWAS loci can help pinpoint targets for therapeutic interventions. Expression studies can disentangle such loci but signals from expression quantitative trait loci (eQTLs) often fail to colocalize—which means that the genetic control of measured expression is not shared w...
Autores principales: | Willett, Julian Daniel Sunday, Lu, Tianyuan, Nakanishi, Tomoko, Yoshiji, Satoshi, Butler-Laporte, Guillaume, Zhou, Sirui, Farjoun, Yossi, Richards, J. Brent |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10511363/ https://www.ncbi.nlm.nih.gov/pubmed/37640912 http://dx.doi.org/10.1007/s00439-023-02590-w |
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