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Allele specific binding of histone modifications and a transcription factor does not predict allele specific expression in correlated ChIP-seq peak-exon pairs

Allele specific expression (ASE) is widespread in many species including cows. Therefore, regulatory regions which control gene expression should show cis-regulatory variation which mirrors this differential expression within the animal. ChIP-seq peaks for histone modifications and transcription fac...

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Detalles Bibliográficos
Autores principales: Prowse-Wilkins, Claire P., Wang, Jianghui, Garner, Josie B., Goddard, Michael E., Chamberlain, Amanda J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10511416/
https://www.ncbi.nlm.nih.gov/pubmed/37730913
http://dx.doi.org/10.1038/s41598-023-42637-6