Surface proteins of Propionibacterium freudenreichii MJ2 inhibit RANKL-induced osteoclast differentiation by lipocalin-2 upregulation and lipocalin-2-mediated NFATc1 inhibition

Osteoclasts degrade bone and osteoclast differentiation has been implicated in bone destruction in rheumatoid arthritis. The dairy bacterium Propionibacterium freudenreichii MJ2 (MJ2) isolated from raw milk inhibits osteoclast differentiation and ameliorates collagen-induced arthritis. This study ai...

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Detalles Bibliográficos
Autores principales: Yeom, Jiah, Ma, Seongho, Yim, Dong Joon, Lim, Young-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10511438/
https://www.ncbi.nlm.nih.gov/pubmed/37730858
http://dx.doi.org/10.1038/s41598-023-42944-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10511438/
https://www.ncbi.nlm.nih.gov/pubmed/37730858
http://dx.doi.org/10.1038/s41598-023-42944-y

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