Fgf signalling triggers an intrinsic mesodermal timer that determines the duration of limb patterning

Complex signalling between the apical ectodermal ridge (AER - a thickening of the distal epithelium) and the mesoderm controls limb patterning along the proximo-distal axis (humerus to digits). However, the essential in vivo requirement for AER-Fgf signalling makes it difficult to understand the exa...

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Detalles Bibliográficos
Autores principales: Sedas Perez, Sofia, McQueen, Caitlin, Stainton, Holly, Pickering, Joseph, Chinnaiya, Kavitha, Saiz-Lopez, Patricia, Placzek, Marysia, Ros, Maria A., Towers, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10511490/
https://www.ncbi.nlm.nih.gov/pubmed/37730682
http://dx.doi.org/10.1038/s41467-023-41457-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10511490/
https://www.ncbi.nlm.nih.gov/pubmed/37730682
http://dx.doi.org/10.1038/s41467-023-41457-6

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